SUMMARY:
This is a discovery research arm of a sponsor company. Our mission is to develop innovative medicines that address significant unmet needs in the treatment of psychiatric and neurological disorders.
We are seeking a highly motivated Scientist to support preclinical stage programs in the portfolio through our mass spectrometry-based Metabolomics and Bioanalysis capabilities. This role involves conducting research on small molecule characterization within the laboratory, ensuring the development and execution of robust analytical methods. The successful candidate will operate and maintain LC/MS systems and contribute to method development and data analysis to support global projects.
Join a dynamic and energetic multi-disciplinary team of qualified colleagues working in a leading CNS specialized drug discovery organization.
KEY RESPONSIBILITIES:
Operate, maintain, and troubleshoot triple quadrupole and Orbitrap LC/MS systems.
Conduct sample preparation for metabolites, lipids and drugs, and perform routine compound screening within projects.
Develop and optimize methods for targeted and untargeted workflows and streamline data analysis pipelines.
Collaborate with project leads and other functional teams to ensure seamless project execution and alignment with organizational objectives.
REQUIRED EDUCATION, QUALIFICATIONS AND SKILLS:
Ph.D. or equivalent work experience in a mass spectrometry-related field, including metabolomics, lipidomics, DMPK, analytical chemistry or biochemistry.
Experience in sample preparation, troubleshooting, and maintenance of triple quadrupole and high-resolution (e.g. Q-ToF, Orbitrap) LC/MS systems.
Familiarity with common bioinformatics approaches for data analysis and visualization.
Demonstrated understanding of principles of mass spectrometry and liquid chromatography.
Ability to critically analyze and effectively communicate data to project leads.
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